Peer-Reviewed Publications as of 9/17/2020
Lee RHC, Couto e Silva A, Hsieh TH, Possoit HE, Citadin CT, Wu CY, Neumann JT, Lin HW. Neuropeptide Y-Mediated Neuroprotection (2020). (Under revision)
Lee, RHC, Grames MS, Wu CYC, Lien CF, Couto e Silva A, Possoit HE, Clemons, GA, Citadin CT, Neumann JT, Pastore D, Lauro D, Della-Morte, D, Lin HW. Upregulation of serum and glucocorticoid-regulated kinase 1 exacerbates brain injury and neurological deficits after cardiac arrest. Am J Physiol Heart Circ Physiol. 2020. (Accepted)
Chen PY, Wu CYC, Clemons GA, Citadin CT, Couto e Silva A, Possoit HE, Azizbayeva R, Forren NE, Liu CH, Rao KNS, Krzywanski DM, Lee RHC, Neumann JT, Lin HW. Stearic acid methyl ester affords neuroprotection and improves functional outcomes after cardiac arrest. Prostaglandins Leukot Essent Fatty Acids. 2020; Aug;159.
Wu CYC, Lopez-Toledano MA, Daak AA, Clemons GA, Citadin CT, Sancilio FD, Rabinowicz AL, Minagar A, Neumann JT, Lee RHC, Lin HW. SC411 treatment can enhance survival in a mouse model of sickle cell disease. Prostaglandins Leukot Essent Fatty Acids. 2020; Jul; 158.
Couto e Silva A, Wu CYC, Citadin CT, Clemons GA, Possoit HE, Grames MS, Lien CF, Minagar A, Lee RHC, Frankel A, Lin HW. Protein Arginine Methyltransferases in Cardiovascular and Neuronal Function. Molecular Neurobiology. 2020; 57(3): 1716-1732.
Lee RHC, Couto e Silva A, Possoit HE, Lerner FM, Chen PY, Azizbayeva R, Citadin CT, Wu CYC, Neumann JT, Lin HW. Palmitic Acid Methyl Ester is a Novel Neuroprotective Agent Against Cardiac Arrest. Prostaglandins Leukot Essent Fatty Acids. 2019; 147:6-14.
Lee RHC, Lee MHH, Wu CY, Couto E Silva A, Possoit HE, Hsieh TH, Minagar A, Lin HW.
Cerebral Ischemia and Neuroregeneration. Neural Regeneration Research. 2018; 13(3):373-385.
Wu CY, Lerner FM, Couto e Silva A, Neumann JT, Neumann JT, Lin HW, Lee RHC. Utilizing the Modified T-Maze to Assess Functional Outcomes after Cardiac Arrest. J Vis Exp. 2018; (131).
Lee RHC, Couto e Silva A, Lerner FM, Wilkins CS, Valido SE, Klein DD, Wu CY, Neumann JT, Della-Morte D, Koslow SH, Minagar A, Lin HW. Interruption of Perivascular Sympathetic Nerves of Cerebral Arteries Offers Neuroprotection Against Ischemia. Am J Physiol Heart Circ Physiol. 2017; 312(1): H182-H188.
Lee RHC, Goyanes Vasquez JJ, Couto e Silva A, Klein DD, Valido SE, Chen JA, Lerner FM, Neumann JT, Wu CY, Lin HW. Fatty acid methyl esters as a potential therapy against cerebral ischemia. Oilseeds & fats Crops and Lipids. 2016; 23(1): D108.
Cohan CH, Neumann JT, Dave KR, Alekseyenko A, Binkert M, Stransky K, Lin HW, Barnes CA, Wright CB, Perez-Pinzon MA. Effect of Cardiac Arrest on Cognitive Impairment and Hippocampal Plasticity in Middle-aged Rats. PLoS One. 2015; 10(5): e0124918.
Lin HW, Gresia VL, Stradecki HM, Alekseyenko A, Dezfulian C, Neumann JT, Dave KR, Perez-Pinzon MA. Protein kinase c delta modulates endothelial nitric oxide synthase after cardiac arrest. J Cereb Blood Flow Metab. 2014; 34(4): 613-620. (Corresponding author)
Lin HW, Saul I, Gresia VL, Neumann JT, Dave KR, Perez-Pinzon MA. Fatty acid methyl esters and solutol HS 15 confers neuroprotection after focal and global cerebral ischemia. Transl Stroke Res. 2014; 5(1):109-117. (Corresponding author)
Lin HW and Perez-Pinzon, MA. The role of fatty acids in the regulation of cerebral vascular function and neuroprotection in ischemia. CNS and Neurological Disorders-Drug Targets. 2013; 12(3):316-324. (Corresponding author)
Lin HW, Yoshida T, Rundek T. Letter by Lin HW et al., Regarding Article, “Nitric Oxide Scavenging of Red Blood Cell Microparticles and Cell-Free Hemoglobin as a Mechanism for the Red Cell Storage Lesion”. Circulation. 2012;125(7): e384. (Corresponding author)
Lin HW, Della-Morte D, Thompson, JW, Gresia, VL, Narayanan SV, DeFazio RA, Raval AP, Saul I, Dave KR, Morris KC, Si ML, Perez-Pinzon MA. Differential effects of delta and epsilon protein kinase C in modulation of post-ischemic cerebral blood flow. Adv Exp Med Biol. 2012; 737: 63-69.
Dave KR, Bhattacharya SK, Saul I, DeFazio RA, Dezfulian C, Lin HW, Raval AP, Perez-Pinzon MA. Activation of protein kinase C delta following cerebral ischemia leads to release of cytochrome c from the mitochondria via Bad pathway. PLoS One. 2011;6(7): e22057.
Lee RH, Liu YQ, Chen PY, Liu CH, Chen MF, Lin HW, Kuo JS, Premkumar LS, Lee TJ. Sympathetic alpha-3 beta-2- nAChRs mediate cerebral neurogenic nitrergic vasodilation in the swine. Am J Physiol Heart Circ Physiol. 2011;301(2):H344-54.
Morris KC, Lin HW, Thompson JW, Perez-Pinzon MA. Pathways for ischemic cytoprotection: Role of sirtuins in caloric restriction, resveratrol and ischemic preconditioning. J Cereb Blood Flow Metab. 2011;31(4):1003-1019.
Lin HW, Thompson JW, Morris KC, Perez-Pinzon MA. Signal Transducers and Activators of Transcription (STATs)-mediated mitochondrial neuroprotection. Antioxid Redox Signal. 2011;14(10):1853-1861.
Della-Morte D, Raval AP, Dave KR, Lin HW, Perez-Pinzon MA. Post-ischemia activation of protein kinase C epsilon protects the hippocampus from cerebral ischemic injury: possible alterations in cerebral blood flow. Neurosci Lett. 2011;487(2):158-162.
DeFazio RA, Levy S, Morales CL, Levy RV, Dave KR, Lin HW, Abaffy T, Watson, BD, Perez-Pinzon MA, Ohanna V. A protocol for characterizing the impact of collateral flow after distal middle cerebral artery occlusion. Transl Stroke Res. 2011; 2(1):112-127.
Lin HW, DeFazio RA, Della Morte D, Thompson JW, Narayanan SV, Raval AP, Saul I, Dave KR, Perez-Pinzon MA. Derangements of post-ischemic cerebral blood flow by protein kinase C delta. Neuroscience. 2010;171(2):566-576.
DeFazio RA, Raval AP, Lin HW, Dave KR, Perez-Pinzon MA. GABA synapses mediate neuroprotection after ischemic and Epsilon PKC preconditioning in the rat hippocampal slice cultures. J Cereb Blood Flow Metab. 2009;29(2):375-384.
Raval AP, Lin HW, Dave KR, DeFazio RA, Della Morte D, Kim EJ, Perez-Pinzon MA. Resveratrol and ischemic preconditioning in the brain. Curr Med Chem. 2008;15(15):1545-1551.
Della Morte D, Abete P, Gallucci F, Scaglione A, D’Ambrosio D, Gargiulo G, De Rosa G, Dave KR, Lin HW, Cacciatore F, Mazzella F, Uomo G, Rundek T, Perez-Pinzon MA, Rengo F. Transient ischemic attack before non-lacunar stroke in the elderly. J Stroke Cerebrovasc Dis. 2008;17(5):257-262.
Lin HW, Liu CZ, Cao D, Chen PY, Chen MF, Lin SZ, Mozayan M, Chen AF, Premkumar LS, Torry DS, Lee TJ. Endogenous methyl palmitate modulates nicotinic receptor-mediated transmission in the superior cervical ganglion. Proc Natl Acad Sci U S A. 2008;105(49):19525-19530.
Invited Book Chapters
- Wu CY, Lee RHC, Lee MHH, Couto e Silva A, Hsieh THH, Possoit H, Brackett AL, Lin HW. (2017) Role of Neuroinflammation in Pathophysiology of Traumatic Brain Injury. In: Alireza Minagar (Ed.), Neuroinflammation (2nd ed.). Amsterdam, Netherlands: Elsevier Publishers Company. (Corresponding author)
- Lee RHC, Wilkins CS, Couto e Silva, A, Valido SE, Wu, CY, Lin HW. (2014) Fatty Acids in Vascular Health. In: Lucas F. Porto (Ed.), Palmitic Acid: Occurrence, Biochemistry and Health Effects (1st ed.). Hauppauge, NY: Nova Science Publishers. (Corresponding author)
- Dave KR, Thompson JW, Neumann JT, Perez-Pinzon MA, Lin HW. (2013) Neurovascular mechanisms of ischemia tolerance against brain injury. In: EH Lo, J Lok, MM Ning, MJ Whalen (Eds.), Vascular Mechanisms in CNS Trauma (1st ed.). NY, NY: Springer Publishing Company.
- Narayanan SV, Morris-Blanco, KC, Perez-Pinzon MA, Lin HW. (2012). Ischemic preconditioning-mediated signaling pathways leads to tolerance against cerebral ischemia. In JM Gidday, MA Perez-Pinzon, & JH Zhang (Eds.), Innate Neuroprotection for Stroke (1st ed.). NY, NY: Springer Publishing Company. (Corresponding author)
- Dave KR, Lin HW, Perez-Pinzon MA. (2012). Tolerance against global cerebral ischemia: experimental strategies, mechanisms and clinical applications. In JM Gidday, MA Perez-Pinzon, & JH Zhang (Eds.), Innate Neuroprotection for Stroke (1st ed.). NY, NY: Springer Publishing Company.